Domain Fishing: a first step in protein comparative modelling
نویسندگان
چکیده
UNLABELLED To optimize the search for structural templates in protein comparative modelling, the query sequence is split into domains. The initial list of templates for each domain, extracted from PFAM plus PDB and SCOP, is then ranked according to sequence identity (%ID), coverage and resolution. If %ID is less than 30, secondary structure matching is used to filter out false templates. AVAILABILITY http://www.bmm.icnet.uk/~3djigsaw/dom_fish
منابع مشابه
Modelling and application: A research domain in mathematics education
Abstract: The main purpose of this paper is introducing modelling and application as a research domain in mathematics education through reviewing related literature. The first purpose of this review is to give a more clear meaning of modelling and application, and base on that, makes the distinction between modelling in mathematics education & modelling in other scientific domains. There are so...
متن کاملCalculation of One-dimensional Forward Modelling of Helicopter-borne Electromagnetic Data and a Sensitivity Matrix Using Fast Hankel Transforms
The helicopter-borne electromagnetic (HEM) frequency-domain exploration method is an airborne electromagnetic (AEM) technique that is widely used for vast and rough areas for resistivity imaging. The vast amount of digitized data flowing from the HEM method requires an efficient and accurate inversion algorithm. Generally, the inverse modelling of HEM data in the first step requires a precise a...
متن کاملA Robust Feedforward Active Noise Control System with a Variable Step-Size FxLMS Algorithm: Designing a New Online Secondary Path Modelling Method
Several approaches have been introduced in literature for active noise control (ANC)systems. Since Filtered-x-Least Mean Square (FxLMS) algorithm appears to be the best choice as acontroller filter. Researchers tend to improve performance of ANC systems by enhancing andmodifying this algorithm. This paper proposes a new version of FxLMS algorithm. In many ANCapplications an online secondary pat...
متن کاملComparative modelling of 3D-structure of Geobacter sp. M21 (a metal reducing bacteria) Mn-Fe superoxide dismutase and its binding properties with bisphenol-A, aminotriazole and ethylene-diurea
Superoxide dismutase play important roles in iron-respiratory bacteria such as Geobacteraceae as an antioxidant defense, and probably an effective enzyme of electron transfer network. Regarding the application of iron-respiratory bacteria in environmental biotechnology particularly biodegradation and bioremediation, understanding the mechanism of inhibition/induction of superoxide dismutase by ...
متن کاملComparative Investigation of R213G Mutation in DNA-Binding Domain of P53 Protein via Molecular Dynamics Simulation
Introduction: P53 is a tumor suppressor protein with numerous missense mutations identified in its gene. These mutations are observed in a vast number of cancers. R213G is one of them which has a role in metastatic lung cancers. In this research, R213G was studied in comparison with the wild type via molecular dynamics simulation. Method: For the three-dimensional structure of the wild-type P53...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Bioinformatics
دوره 18 8 شماره
صفحات -
تاریخ انتشار 2002